Matthew J. Pierson, MD



Areas of Specialty

Benign and malignant brain tumor surgery

Skull base neurosurgery

Cerebrovascular neurosurgery including aneurysms, arteriovenous malformation (AVM), and cerebrovascular bypass surgery

Minimally invasive spine surgery

Endoscopic Neurosurgery

Degenerative spine disease

Spine and spinal cord tumors

Peripheral Nerve Surgery

Stereotactic Radiosurgery

Trauma surgery and neurocritical care


Dr. Pierson is a Kansas born native and received his medical school degree from the University of Kansas in 2012. 

He completed his neurosurgical residency at Saint Louis University and also completed a fellowship in cerebrovascular and skull base neurosurgery at Saint Louis University.

Education and Credentials

B.S., Kansas State University, 2004-2008
Manhattan, Kansas
Biology, Magna Cum Laude

M.D., University of Kansas School of Medicine
Kansas City, KS May 2008-2012

Internship in General Surgery, July 2012 to June 2013
Department of Surgery
Saint Louis University
Saint Louis, MO

Resident in Neurological Surgery, July 2013 to June 2019
Department of Neurological Surgery
Saint Louis University
Saint Louis, MO

Fellowship in Cerebrovascular and Skull Base Surgery
July 2019 – June 2020
Department of Neurologic Surgery
Saint Louis University
Saint Louis, MO

Membership & Awards

Board Status
American Board of Neurological Surgery Written Examination –Passed 2016

Professional Society Membership
Resident Member of American Association of Neurological Surgeons – July 2013 to June 2019

Committee Memberships:
Saint Louis University Hospital Ethics Committee – Member, 2014 to present

2016 Saint Louis University Hospital Caring Physician Award
2018 SSM Health Saint Louis University Hospital “I am the Mission” recipient

Peer Reviewed Journal Publications

Pierson M, Birinyi PV, Bhimireddy S, Coppens JR. Analysis of Decompressive Craniectomies with Subsequent Cranioplasties in the Presence of Collagen Matrix Dural Substitute and Polytetrafluoroethylene as an Adhesion Preventative Material. World Neurosurg. 2016 Feb;86:153-60. doi: 10.1016/j.wneu.2015.09.078. Epub 2015 Dec 22. PubMed PMID: 26433096.

Marwaha N, Batanian JR, Coppens JR, Pierson MJ, Richards-Yutz J, Ebrahimzadeh J, Ganguly A, Guzman MA. Subcutaneous melanocytoma mimicking a lipoma: A rare presentation of a rare neoplasm with histological, immunohistochemical, cytogenetic and molecular characterization. J Cutan Pathol. 2016 Aug 30. doi: 10.1111/cup.12808. [Epub ahead of print] PubMed PMID: 27573466.

Abdulrauf SI, Ashour AM, Marvin E, Coppens J, Kang B, Hsieh TY, Nery B, Penanes JR, Alsahlawi AK, Moore S, Abou Al-Shaar H, Kemp J, Chawla K, Sujijantarat N, Najeeb A, Parkar N, Shetty V, Vafaie T, Antisdel J, Mikulec TA, Edgell R, Lebovitz J, Pierson M, Pires de Aguiar PH, Buchanan P, Di Cosola A, Stevens G. Proposed clinical internal carotid artery classification system. J Craniovertebr Junction Spine. 2016 Jul-Sep;7(3):161-70. doi: 10.4103/0974-8237.188412.

Pierson M, Marwaha N, Guzman M, Mikulec AA, Coppens JR. Multifocal melanocytoma of the posterior fossa and subcutaneous scalp in the absence of neurocutaneous melanosis. Surg Neurol Int. 2016 Sep 1;7(Suppl 23):S591-5. doi: 10.4103/2152-7806.189728. eCollection 2016. PubMed PMID: 27656317; PubMed Central PMCID: PMC5025953.

Pierson MJ, Elbabaa SK. Endoscope-Assisted Management of Syndromic and Nonsyndromic Craniosynostosis Part I—Introduction and Pathophysiology. Contemporary Neurosurgery. 38(16):1-3, November 15, 2016.

Pierson MJ, Elbabaa SK. Endoscope-Assisted Management of Syndromic and Nonsyndromic Craniosynostosis Part II—Nonsyndromic Craniosynostosis: Sagittal, Unilateral Coronal, Metopic, and Lambdoid Sutures. Contemporary Neurosurgery. 38(17): 1-5, November 30, 2016.

Pierson MJ, Elbabaa SK. Endoscope-Assisted Management of Syndromic and Nonsyndromic Craniosynostosis Part III—Syndromic Craniosynostosis. Contemporary Neurosurgery. 38(18): 1-5, December 30, 2016.

Pierson MJ, Wehrmann D, Albers JA, El Tecle NE, Costa D, Elbabaa SK. Programmable shunt valve interactions with osseointegrated hearing devices. J Neurosurg Pediatr. 2017 Feb 10:1-7. doi: 10.3171/2016.11.PEDS16501.

Elbabaa SK, Gildehaus AM, Pierson MJ, Albers JA, Vlastos EJ. First 60 fetal in-utero myelomeningocele repairs at Saint Louis Fetal Care Institute in the post-MOMS trial era: hydrocephalus treatment outcomes (endoscopic third ventriculostomy versus ventriculo-peritoneal shunt). Childs Nerv Syst. 2017 Jul;33(7):1157-1168. doi: 10.1007/s00381-017-3428-8. Epub 2017 May 3.

Yaltırık K, El Tecle NE, Pierson MJ, Puryear A, Atalay B, Elbabaa SK. Management of concomitant scoliosis and tethered cord syndrome in non-spina bifida pediatric population. Childs Nerv Syst. 2017 Jul 10. doi: 10.1007/s00381-017-3504-0. [Epub ahead of print]

Sujijantarat N, Pierson MJ, Kemp J, Coppens JR. Staged Trapping of Traumatic Basilar Trunk Pseudoaneurysm: Case Report and Review of Literature. World Neurosurg. 2017 Sep 1. pii: S1878-8750(17)31445-6. doi: 10.1016/j.wneu.2017.08.144. [Epub ahead of print]

Sujijantarat N, Tecle NE, Pierson M, Urquiaga JF, Quadri NF, Ashour AM, Khan MQ, Buchanan P, Kumar A, Feen E, Coppens J. Trans-Sulcal Endoport-Assisted Evacuation of Supratentorial Intracerebral Hemorrhage: Initial Single-Institution Experience Compared to Matched Medically Managed Patients and Effect on 30-day Mortality. Oper Neurosurg. 2017 Jul 22. doi: 10.1093/ons/opx161. [Epub ahead of print]

Abdulrauf SI, Urquiaga JF, Patel R, Albers JA, Sampat VB, Baumer M, Marvin E, Pierson M, Kragel R, Walsh J. Awake Microvascular Decompression for Trigeminal Neuralgia: Concept and Initial Results. World Neurosurg. 2018 May;113:e309-e313. doi: 10.1016/j.wneu.2018.02.019. Epub 2018 Feb 13. PMID: 29452326

Textbooks & Book Chapters

Birinyi PV, El Tecle N, Marvin E, Zamora C, Prayson R, Elbabaa SK, Pierson M, Huynh K. The Comprehensive Neurosurgery Board Preparation Book: Illustrated Questions and Answers. New York, NY: Thieme Publishing, 2016.

Pierson MJ, Elbabaa SK: Hydrocephalus and Myelomeningocele. In Cinalli G, Ozek M, Saint-Rose C (Eds): Pediatric Hydrocephalus (2nd Edition). Springer Publisher, 2019.

Pierson M, Edgell R, Elbabaa SK. Vein of Galen Malformation. In: Neurosurgery Case Review, 2nd Edition. New York, NY: Thieme Publishing. (in process)

Oral Presentations

Pierson MJ, Gildehaus A, Buchanan PM, Vlastos EJ, Elbabaa SK. Microneurosurgical Placode Tulbularization on Reducing Spinal Cord Tethering and Inclusion Cysts Following 60 Fetal Myelomeningocele Repairs. AANS/CNS Section on Pediatric Neurosurgery 46th Annual Meeting. Houston, TX, December 1, 2017.

Poster Presentations

Pierson MJ, Whermann D, Albers JA, El Tecle N, Costa DJ, Elbabaa SK. Programmable shunt valve interactions with osseointegrated hearing devices. AANS/CNS Section on Pediatric Neurosurgery 45th Annual Meeting. Orlando, FL, December 5-8, 2016.

Invited Lecturer

Pierson M. Glasgow Coma Scale, Trauma Grand Rounds, August 6th, 2014. St. John’s Mercy Hospital, St. Louis, Missouri.

Hear From Dr. Pierson’s Patients


Dr. Pierson is great at listening, asking good questions, offering options, knowing the subject matter, and also doing more research/consulting. Never feel hurried. I trust his opinions…and would give him a gold star.


Professionalism, empathy, bedside manner, surgical skill, very humble, and like a real person. We hope to never need this specialized care again but if we did Dr. Pierson would be the first choice.


This was the first visit with Dr. Pierson. He isn’t sure yet what the exact problem is but he assured us he would find out what is wrong. He ordered tests. Dr. Pierson shows compassion and seems dedicated to finding the problem.


Excellent service.


He is a miracle worker!